Genetic Health Profile (Muhdo)

Comprehensive DNA-based analysis revealing genetic predispositions across fitness, nutrition, recovery, sleep, and health domains.

Genetic Health Profile (Muhdo)

Table of contents

Basic data

The Comprehensive Genetic Health Profile (Muhdo) is an advanced DNA test that analyzes hundreds of single nucleotide polymorphisms (SNPs) to uncover individual genetic predispositions influencing physical performance, nutrition, vitamin metabolism, recovery capacity, mental resilience, and long-term health risks.

This test helps users understand how their genes may affect traits such as muscle power and endurance, carbohydrate and fat metabolism, inflammatory response, sleep quality, stress resilience, and susceptibility to injury. Unlike clinical diagnostics, it does not measure current biomarker levels but provides insights into inherent tendencies — guiding more effective personalization of training, supplementation, and lifestyle strategies.

The Muhdo platform integrates genetic science with lifestyle coaching, offering a user-friendly report that translates complex genomic data into clear, actionable recommendations for health optimization.

Category: Genetics

Level: Advanced

Usefulness: Medium

Level

Advanced

This is an advanced-level diagnostic suitable for individuals who have already optimized lifestyle fundamentals (diet, exercise, sleep) and want to refine their health strategy through genetic insights. The test provides valuable context for personalized interventions but requires professional interpretation to avoid overemphasis on single-gene effects.

Usefulness

Medium

The Muhdo DNA profile provides a holistic overview of genetic predispositions that influence key longevity and performance factors. It’s best used as a complementary tool alongside bloodwork, wearable data, and lifestyle tracking.
Genetic insight for personalization

Identifies how your body may respond to nutrition, training, and stress — enabling better-tailored health strategies.

Predictive rather than diagnostic

Highlights predispositions rather than active conditions, making it useful for prevention and lifestyle design.

Broad coverage

Covers fitness, recovery, micronutrient metabolism, sleep, stress, aging, injury risk, and cognitive performance.

How it works

Muhdo analyzes DNA extracted from a saliva sample using genotyping arrays that examine hundreds of genetic variants (SNPs) linked to key biological processes.
Sample collection

A saliva sample is collected at home using a sterile kit and sent to the Muhdo laboratory for DNA extraction.

SNP genotyping

Genetic variants are identified through microarray analysis, covering markers associated with metabolism, recovery, inflammation, and neuromuscular function.

Report generation

Results are aggregated into personalized reports that group SNPs into lifestyle-relevant categories like nutrition, exercise, vitamins, stress, and longevity.

Measures

The Muhdo report summarizes predispositions across multiple biological domains, highlighting potential genetic strengths and vulnerabilities.
Fitness and physical traits

Power and endurance potential, VO₂max predisposition, recovery speed, muscle fiber composition, and injury risk.

Nutrition and metabolism

Genetic tendencies affecting carbohydrate, fat, and protein metabolism, as well as weight gain and fat distribution.

Vitamins and micronutrients

Predispositions for deficiencies in vitamin D, B12, folate, magnesium, selenium, and other essential nutrients.

Gut health

Predispositions for gluten intolerance, irritable bowel syndrome (IBS), gum disease risk, and the impact of stress or caffeine on digestive health.

Cardiovascular health

Genetic risk for hypertension, arrhythmia, lipid imbalance (LDL/HDL), and cardiovascular disease; sodium sensitivity.

Immunity and inflammation

Immune response potential, inflammation tendency, and response to vitamins and minerals (vitamin D, B-group, selenium, C). Includes markers like PTPN22 associated with immune regulation.

Vision and eye health

Risk of cataract or glaucoma, beta-carotene conversion efficiency, and predispositions to age-related vision decline.

Skin health and aging

Predispositions related to skin aging, collagen turnover, pigmentation, photoaging, and skin sensitivity to gluten or sunlight.

Muscular system

Myostatin-related muscle mass potential, testosterone baseline levels, inflammation-related soreness response, and CoQ10 deficiency risk.

Stress and mental health

Genes linked to stress resilience, focus, memory, and cognitive performance, including COMT variants (“warrior” vs “sensitive” type).

Reliability

Genetic data are stable and reproducible, but the interpretation of gene–trait associations evolves with ongoing scientific research.
Analytical accuracy

DNA sequencing and SNP genotyping are highly reliable; errors are rare when laboratory quality controls are met.

Interpretation variability

The predictive value of individual SNPs varies; most health outcomes depend on multiple genes and lifestyle factors.

Limitations

The Muhdo DNA Health Profile provides insight into genetic predispositions but does not diagnose or measure actual physiological states.
Context-dependent value

Results should always be interpreted alongside lifestyle data and clinical tests — genetics alone explain only part of health outcomes.

No current biomarker data

The test reveals tendencies but not current vitamin levels, inflammation, or hormonal balance.

Overinterpretation risk

Single genetic variants rarely determine outcomes; complex interactions and epigenetic factors also play major roles.

Frequency

Suggested cadence

One-time test; genetic data remain stable throughout life. Optional re-analysis if new panels or scientific updates are introduced.

Cost

Typical costs

Approximately €150–300, depending on region and whether epigenetic modules or coaching add-ons are included.

Availability

Where available

Offered worldwide through Muhdo’s online platform and affiliated longevity and wellness clinics.

Preparation

How to prepare

Avoid eating, drinking, or brushing teeth for at least 30 minutes before providing the saliva sample to prevent DNA contamination.

Interpretation

The report provides color-coded insights into genetic predispositions across multiple areas. Results should be interpreted as potential tendencies, not certainties.
Green (favorable)

Indicates genetically advantageous or balanced predispositions — e.g., strong recovery capacity or normal metabolism.

Yellow (neutral/moderate)

Suggests average genetic tendency — modifiable through lifestyle choices such as training, nutrition, or recovery.

Red (unfavorable)

Highlights potential vulnerabilities — e.g., higher risk of injury or lower vitamin absorption — warranting targeted interventions.

Alternatives

3x4 Genetics Blueprint

Focuses on functional genomics for personalized nutrition and exercise guidance.

DNAFit Fitness & Diet Pro

Provides a similar interpretation of fitness and nutrition genetics with a focus on actionable recommendations.

FAQ

Does the Muhdo test diagnose diseases?

No. It identifies genetic tendencies that may influence health outcomes but does not diagnose or confirm disease.

Can lifestyle changes override my genetic predispositions?

In most cases, yes. Genes set potential limits, but lifestyle, training, and nutrition largely determine real outcomes.

Is it worth retesting over time?

The DNA sequence doesn’t change, but retesting may be useful if Muhdo updates its algorithm or adds new evidence-based traits.