Telomere Length Test (TeloNostiX)

Laboratory DNA-based test measuring telomere length as a molecular marker of cellular aging.

Telomere Length Test (TeloNostiX)

Table of contents

Basic data

The Telomere Length Test (TeloNostiX) evaluates the average length of telomeres — the protective DNA sequences at the ends of chromosomes — using a high-precision method called High Throughput Single Telomere Length Analysis (HT-STELA). Telomeres naturally shorten as cells divide and age, and their length is influenced by genetics, lifestyle, and environmental factors. This test provides an estimate of biological aging at the cellular level by comparing your telomere length with population-based percentiles for your chronological age.

Shorter telomeres are associated with accelerated cellular aging and increased risk for chronic diseases, while longer telomeres typically reflect better cellular maintenance and resilience. However, telomere dynamics are complex and may vary significantly between tissues and individuals.

Category: Epigenetics

Level: Advanced

Usefulness: Low

Level

Advanced

This is an advanced-level molecular test designed for users already experienced with foundational health optimization and interested in deep molecular insights into biological aging. Telomere length analysis provides a broad indication of cellular aging but should be interpreted as part of a larger longevity assessment framework, alongside epigenetic and physiological markers.

Usefulness

Low

The test measures average telomere length from a DNA sample to estimate the degree of cellular aging. While valuable for scientific and personal tracking, it has limited standalone diagnostic utility.
Insight into biological aging

Provides a molecular snapshot of how rapidly your cells may be aging relative to your chronological age.

Lifestyle feedback

Can motivate positive lifestyle interventions related to stress management, sleep, diet, and exercise, which affect telomere maintenance.

How it works

Telomeres are repetitive DNA sequences (TTAGGG) that protect chromosome ends. The test measures their average length from your DNA sample using a quantitative laboratory technique.
Sample collection

A dried blood spot (DBS) or venous blood sample is collected and sent to the TeloNostiX laboratory under controlled pre-examination conditions.

HT-STELA measurement

The High Throughput Single Telomere Length Analysis (HT-STELA) method determines the mean telomere length from three independent DNA reactions. The average value and coefficient of variation (CV%) ensure measurement reliability.

Measures

The report presents your mean telomere length in kilobases (kb) and compares it with age-matched population percentiles to indicate your relative cellular aging status.
Mean Telomere Length

The average telomere length measured across multiple DNA reactions, expressed in kilobases (kb).

Percentile Range

Position of your result compared with reference population (e.g., 10th–50th percentile indicates normal age-matched range).

Reliability

The HT-STELA technique offers high analytical precision with a typical measurement uncertainty of ±0.194 kb. Each test includes a quality control check based on the coefficient of variation (CV%).
Repeatability

Results are reproducible if samples are collected under identical conditions; variability may increase due to biological fluctuation or sample handling.

Sensitivity to sample quality

Inaccurate sample collection, degradation, or contamination can affect DNA integrity and lead to unreliable readings.

Limitations

The Telomere Length Test is not a diagnostic or predictive medical tool. It should be interpreted as a general indicator of molecular aging trends.
High inter-individual variability

Telomere length varies widely among individuals and tissues; results should not be over-interpreted or compared across labs.

Limited clinical translation

Shorter telomeres correlate with aging but do not directly indicate disease presence or predict lifespan.

Frequency

Suggested cadence

Repeat testing every 12–24 months to observe long-term trends in cellular aging and assess whether lifestyle changes influence telomere dynamics.

Cost

Typical costs

Approximately €250–400 depending on provider and shipping; includes DNA extraction, HT-STELA analysis, and report generation.

Availability

Where available

Conducted by the TeloNostiX laboratory and available through longevity clinics.

Preparation

How to prepare

Follow the blood collection kit instructions carefully. Avoid alcohol, smoking, or vigorous exercise 24 hours before sampling. Ensure proper labeling and timely shipment.

Interpretation

The report compares your telomere length to population averages to indicate whether your cellular aging rate is within, faster, or slower than typical for your age.
Within normal range

Suggests healthy cellular aging and balanced lifestyle factors. Continue maintaining supportive habits.

Below average range

Indicates potentially accelerated cellular aging; review lifestyle factors like stress, sleep, and oxidative load.

Alternatives

DNA Methylation Clocks (e.g., DunedinPACE, TrueAge)

Assess biological age more comprehensively by analyzing DNA methylation patterns across the genome.

Blood Age (Deep Longevity)

AI-based biological age model derived from blood biomarker patterns rather than direct DNA structure.

FAQ

What is a good telomere length?

There is no universal ‘ideal’ length. Most healthy adults fall within 4–8 kb, but optimal range depends on genetics and laboratory methodology.

Can lifestyle changes affect telomere length?

Yes. Physical activity, balanced diet, stress reduction, and adequate sleep are linked with slower telomere shortening and improved cellular health.

Is this test suitable for medical diagnosis?

No. It is a research-grade longevity assessment tool and should not replace clinical diagnostics or physician advice.